Human UDP-glucuronosyltransferase UGT2A2: cDNA construction, expression, and functional characterization in comparison with UGT2A1 and UGT2A3

OBJECTIVES: Characterize the expression and glucuronidation activities of the human UDP-glucuronosyltransferase (UGT) 2A2. METHODS: UGT2A1 was cloned from nasal mucosa mRNA. Synthetic cDNA for UGT2A2 was constructed assuming exon sharing between UGT2A1 and UGT2A2 (Mackenzie et al., Pharmacogenetics...

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Bibliografiske detaljer
Main Authors: Sneitz, Nina, Court, Michael H., Zhang, Xiuling, Laajanen, Kaisa, Yee, Karen K., Dalton, Pamela, Ding, Xinxin, Finel, Moshe
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928392/
https://ncbi.nlm.nih.gov/pubmed/19858781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3283330767
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