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Novel polymorphic human UDP-glucuronosyltransferase (UGT) 2A3: Cloning, functional characterization of enzyme variants, comparative tissue expression, and gene induction

UDP-glucuronosyltransferases (UGTs) are critical to the detoxification of numerous drugs, environmental pollutants, and endogenous molecules. However as yet not all of the human UGTs have been cloned and characterized. cDNA clones from the UGT2A3 gene (located on chromosome 4q13) were isolated using...

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Detalhes bibliográficos
Main Authors: Court, Michael H., Hazarika, Suwagmani, Krishnaswamy, Soundararajan, Finel, Moshe, Williams, J. Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574548/
https://ncbi.nlm.nih.gov/pubmed/18523138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.045500
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