Glucuronidation of the steroid enantiomers ent-17β-estradiol, ent-androsterone and ent-etiocholanolone by the human UDP-glucuronosyltransferases

Steroids enantiomers are interesting compounds for detailed exploration of drug metabolizing enzymes, such as the UDP-glucuronosyltransferases (UGTs). We have now studied the glucuronidation of the enantiomers of estradiol, androsterone and etiocholanolone by the 19 human UGTs of subfamilies 1A, 2A...

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Bibliographic Details
Main Authors: Sneitz, Nina, Krishnan, Kathiresan, Covey, Douglas F., Finel, Moshe
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234363/
https://ncbi.nlm.nih.gov/pubmed/21899827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2011.08.008
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