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The Use of Family Relationships and Linkage Disequilibrium to Impute Phase and Missing Genotypes in Up to Whole-Genome Sequence Density Genotypic Data
A novel method, called linkage disequilibrium multilocus iterative peeling (LDMIP), for the imputation of phase and missing genotypes is developed. LDMIP performs an iterative peeling step for every locus, which accounts for the family data, and uses a forward–backward algorithm to accumulate inform...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Genetics Society of America
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2927768/ https://ncbi.nlm.nih.gov/pubmed/20479147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.113936 |
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