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The Use of Family Relationships and Linkage Disequilibrium to Impute Phase and Missing Genotypes in Up to Whole-Genome Sequence Density Genotypic Data
A novel method, called linkage disequilibrium multilocus iterative peeling (LDMIP), for the imputation of phase and missing genotypes is developed. LDMIP performs an iterative peeling step for every locus, which accounts for the family data, and uses a forward–backward algorithm to accumulate inform...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2927768/ https://ncbi.nlm.nih.gov/pubmed/20479147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.113936 |
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