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Imputation of Missing Genotypes From Sparse to High Density Using Long-Range Phasing
Related individuals share potentially long chromosome segments that trace to a common ancestor. We describe a phasing algorithm (ChromoPhase) that utilizes this characteristic of finite populations to phase large sections of a chromosome. In addition to phasing, our method imputes missing genotypes...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3176129/ https://ncbi.nlm.nih.gov/pubmed/21705746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.128082 |
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