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Novel Naphthalene-Based Inhibitors of Trypanosoma brucei RNA Editing Ligase 1

BACKGROUND: Neglected tropical diseases, including diseases caused by trypanosomatid parasites such as Trypanosoma brucei, cost tens of millions of disability-adjusted life-years annually. As the current treatments for African trypanosomiasis and other similar infections are limited, new therapeutic...

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Detalhes bibliográficos
Main Authors: Durrant, Jacob D., Hall, Laurence, Swift, Robert V., Landon, Melissa, Schnaufer, Achim, Amaro, Rommie E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927429/
https://ncbi.nlm.nih.gov/pubmed/20808768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000803
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