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Discovery of drug-like inhibitors of an essential RNA-editing ligase in Trypanosoma brucei
Trypanosomatid RNA editing is a unique process and essential for these organisms. It therefore represents a drug target for a group of protozoa that includes the causative agents for African sleeping sickness and other devastating tropical and subtropical diseases. Here, we present drug-like inhibit...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2577703/ https://ncbi.nlm.nih.gov/pubmed/18981420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805820105 |
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