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Towards the development of novel Trypanosoma brucei RNA editing ligase 1 inhibitors

BACKGROUND: Trypanosoma brucei (T. brucei) is an infectious agent for which drug development has been largely neglected. We here use a recently developed computer program called AutoGrow to add interacting molecular fragments to S5, a known inhibitor of the validated T. brucei drug target RNA editin...

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Detalhes bibliográficos
Main Authors: Durrant, Jacob D, McCammon, J Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196686/
https://ncbi.nlm.nih.gov/pubmed/21878090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-11-9
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