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A novel high-throughput activity assay for the Trypanosoma brucei editosome enzyme REL1 and other RNA ligases

The protist parasite Trypanosoma brucei causes Human African trypanosomiasis (HAT), which threatens millions of people in sub-Saharan Africa. Without treatment the infection is almost always lethal. Current drugs for HAT are difficult to administer and have severe side effects. Together with increas...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Zimmermann, Stephan, Hall, Laurence, Riley, Sean, Sørensen, Jesper, Amaro, Rommie E., Schnaufer, Achim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756849/
https://ncbi.nlm.nih.gov/pubmed/26400159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv938
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