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A novel high-throughput activity assay for the Trypanosoma brucei editosome enzyme REL1 and other RNA ligases

The protist parasite Trypanosoma brucei causes Human African trypanosomiasis (HAT), which threatens millions of people in sub-Saharan Africa. Without treatment the infection is almost always lethal. Current drugs for HAT are difficult to administer and have severe side effects. Together with increas...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Zimmermann, Stephan, Hall, Laurence, Riley, Sean, Sørensen, Jesper, Amaro, Rommie E., Schnaufer, Achim
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756849/
https://ncbi.nlm.nih.gov/pubmed/26400159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv938
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