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A novel high-throughput activity assay for the Trypanosoma brucei editosome enzyme REL1 and other RNA ligases

The protist parasite Trypanosoma brucei causes Human African trypanosomiasis (HAT), which threatens millions of people in sub-Saharan Africa. Without treatment the infection is almost always lethal. Current drugs for HAT are difficult to administer and have severe side effects. Together with increas...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zimmermann, Stephan, Hall, Laurence, Riley, Sean, Sørensen, Jesper, Amaro, Rommie E., Schnaufer, Achim
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756849/
https://ncbi.nlm.nih.gov/pubmed/26400159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv938
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