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Design of polyzinc finger peptides with structured linkers

Zinc finger domains are perhaps the most versatile of all known DNA binding domains. By fusing up to six zinc finger modules, which normally recognize up to 18 bp of DNA, designer transcription factors can be produced to target unique sequences within large genomes. However, not all continuous DNA s...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Moore, Michael, Choo, Yen, Klug, Aaron
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2001
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29274/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11171968/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.4.1432
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