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Design of polyzinc finger peptides with structured linkers

Zinc finger domains are perhaps the most versatile of all known DNA binding domains. By fusing up to six zinc finger modules, which normally recognize up to 18 bp of DNA, designer transcription factors can be produced to target unique sequences within large genomes. However, not all continuous DNA s...

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Bibliografske podrobnosti
Main Authors: Moore, Michael, Choo, Yen, Klug, Aaron
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC29274/
https://ncbi.nlm.nih.gov/pubmed/11171968
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