Design of polyzinc finger peptides with structured linkers
Zinc finger domains are perhaps the most versatile of all known DNA binding domains. By fusing up to six zinc finger modules, which normally recognize up to 18 bp of DNA, designer transcription factors can be produced to target unique sequences within large genomes. However, not all continuous DNA s...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2001
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29274/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11171968/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.4.1432 |
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