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Design of polyzinc finger peptides with structured linkers

Zinc finger domains are perhaps the most versatile of all known DNA binding domains. By fusing up to six zinc finger modules, which normally recognize up to 18 bp of DNA, designer transcription factors can be produced to target unique sequences within large genomes. However, not all continuous DNA s...

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Bibliografiska uppgifter
Huvudupphovsmän: Moore, Michael, Choo, Yen, Klug, Aaron
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2001
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC29274/
https://ncbi.nlm.nih.gov/pubmed/11171968
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