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Auto-inhibition of Human Dicer by its Internal Helicase Domain
Dicer, a member of the Ribonuclease III family of enzymes, processes double-stranded RNA substrates into ~21-27 nucleotide products that trigger sequence-directed gene silencing by RNA interference (RNAi). Although the mechanism of RNA recognition and length-specific cleavage by Dicer has been estab...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2927216/ https://ncbi.nlm.nih.gov/pubmed/18508075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.05.005 |
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