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Action of the Chaperonin GroEL/ES on a Non-Native Substrate Observed with Single-Molecule FRET
The double-ring-shaped chaperonin GroEL binds a wide range of non-native polypeptides within its central cavity and, together with its cofactor GroES, assists their folding in an ATP-dependent manner. While the conformational cycle of GroEL/ES has been extensively studied, little is known about how...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2927214/ https://ncbi.nlm.nih.gov/pubmed/20600107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.06.050 |
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