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B-Cell-Delivered Gene Therapy Induces Functional T Regulatory Cells and Leads to a Loss of Antigen-Specific Effector Cells
Previous reports have shown that B-cell-mediated gene therapy can induce tolerance in several animal models for autoimmune diseases and inhibitory antibody formation in hemophilia A mice. We know from our previous work that the induction of tolerance following B-cell therapy is dependent upon CD25(+...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Nature Publishing Group
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2927073/ https://ncbi.nlm.nih.gov/pubmed/20485267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.95 |
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