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Prophylactic immune tolerance induced by changing the ratio of antigen-specific effector to regulatory T cells
BACKGROUND: Gene and protein replacement therapies for inherited protein deficiencies such as hemophilia or lysosomal storage disorders are limited by deleterious immune responses directed against their respective therapeutic protein. Therefore, the development of protocols preventing such responses...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2981868/ https://ncbi.nlm.nih.gov/pubmed/19583824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2009.03548.x |
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