Macrophage-mediated GDNF Delivery Protects Against Dopaminergic Neurodegeneration: A Therapeutic Strategy for Parkinson's Disease

Glial cell line–derived neurotrophic factor (GDNF) has emerged as the most potent neuroprotective agent tested in experimental models for the treatment of Parkinson's disease (PD). However, its use is hindered by difficulties in delivery to the brain due to the presence of the blood–brain barri...

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Bibliographische Detailangaben
Hauptverfasser: Biju, KC, Zhou, Qing, Li, Guiming, Imam, Syed Z, Roberts, James L, Morgan, William W, Clark, Robert A, Li, Senlin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927058/
https://ncbi.nlm.nih.gov/pubmed/20531393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.107
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