Macrophage-mediated GDNF Delivery Protects Against Dopaminergic Neurodegeneration: A Therapeutic Strategy for Parkinson's Disease

Glial cell line–derived neurotrophic factor (GDNF) has emerged as the most potent neuroprotective agent tested in experimental models for the treatment of Parkinson's disease (PD). However, its use is hindered by difficulties in delivery to the brain due to the presence of the blood–brain barri...

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Detalhes bibliográficos
Main Authors: Biju, KC, Zhou, Qing, Li, Guiming, Imam, Syed Z, Roberts, James L, Morgan, William W, Clark, Robert A, Li, Senlin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927058/
https://ncbi.nlm.nih.gov/pubmed/20531393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.107
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