Disrupting 5-HT(2A) Receptor/PDZ Protein Interactions Reduces Hyperalgesia and Enhances SSRI Efficacy in Neuropathic Pain

Antidepressants are one of the first-line treatments for neuropathic pain. Despite the influence of serotonin (5-hydroxytryptamine, 5-HT) in pain modulation, selective serotonin reuptake inhibitors (SSRIs) are less effective than tricyclic antidepressants. Here, we show, in diabetic neuropathic rats...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pichon, Xavier, Wattiez, Anne S, Becamel, Carine, Ehrlich, Ingrid, Bockaert, Joel, Eschalier, Alain, Marin, Philippe, Courteix, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927054/
https://ncbi.nlm.nih.gov/pubmed/20531396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.101
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados