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Physical Interaction of Calmodulin with the 5-Hydroxytryptamine(2C) Receptor C-Terminus Is Essential for G Protein-independent, Arrestin-dependent Receptor Signaling

The serotonin (5-hydroxytryptamine; 5-HT)(2C) receptor is a G protein-coupled receptor (GPCR) exclusively expressed in CNS that has been implicated in numerous brain disorders, including anxio-depressive states. Like many GPCRs, 5-HT(2C) receptors physically interact with a variety of intracellular...

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Autors principals: Labasque, Marilyne, Reiter, Eric, Becamel, Carine, Bockaert, Joël, Marin, Philippe
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575147/
https://ncbi.nlm.nih.gov/pubmed/18768750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-04-0422
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