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Presynaptic serotonin 2A receptors modulate thalamocortical plasticity and associative learning

Higher-level cognitive processes strongly depend on a complex interplay between mediodorsal thalamus nuclei and the prefrontal cortex (PFC). Alteration of thalamofrontal connectivity has been involved in cognitive deficits of schizophrenia. Prefrontal serotonin (5-HT)(2A) receptors play an essential...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Barre, Alexander, Berthoux, Coralie, De Bundel, Dimitri, Valjent, Emmanuel, Bockaert, Joël, Marin, Philippe, Bécamel, Carine
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791007/
https://ncbi.nlm.nih.gov/pubmed/26903620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1525586113
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