Radiation Sensitivity and Tumor Susceptibility in ATM Phospho-Mutant ATF2 Mice

The transcription factor ATF2 was previously shown to be an ATM substrate. Upon phosphorylation by ATM, ATF2 exhibits a transcription-independent function in the DNA damage response through localization to DNA repair foci and control of cell cycle arrest. To assess the physiological significance of...

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Hlavní autoři: Li, Shuangwei, Ezhevsky, Sergei, Dewing, Antimone, Cato, Matthew H., Scortegagna, Marzia, Bhoumik, Anindita, Breitwieser, Wolfgang, Braddock, Demetrious, Eroshkin, Alexey, Qi, Jianfei, Chen, Meifan, Kim, Jae-Young, Jones, Stephen, Jones, Nic, Rickert, Robert, Ronai, Ze’ev A.
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2010
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926982/
https://ncbi.nlm.nih.gov/pubmed/20740050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910370700
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