Identification of a Polycystin-1 Cleavage Product, P100, That Regulates Store Operated Ca(2+) Entry through Interactions with STIM1

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a genetic disorder resulting in large kidney cysts and eventual kidney failure. Mutations in either the PKD1 or PKD2/TRPP2 genes and their respective protein products, polycystin-1 (PC1) and polycystin-2 (PC2) result in ADPKD. PC2 is known to f...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Woodward, Owen M., Li, Yun, Yu, Shengqiang, Greenwell, Patrick, Wodarczyk, Claas, Boletta, Alessandra, Guggino, William B., Qian, Feng
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925899/
https://ncbi.nlm.nih.gov/pubmed/20808796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012305
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires