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Molecular Determinants for STIM1 Activation During Store Operated Ca(2+) Entry
BACKGROUND: STIM/ORAI-mediated store-operated Ca(2+) entry (SOCE) mediates a myriad of Ca(2+)-dependent cellular activities in mammals. Genetic defects in STIM1/ORAI1 lead to devastating severe combined immunodeficiency; whereas gain-of-function mutations in STIM1/ORAI1 are intimately associated wit...
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| Udgivet i: | Curr Mol Med |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5563273/ https://ncbi.nlm.nih.gov/pubmed/28231751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1566524017666170220103731 |
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