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YB-1 ALTERS MT1-MMP TRAFFICKING AND STIMULATES MCF-7 BREAST TUMOR INVASION AND METASTASIS

YB-1 is a member of the cold shock domain family, with complex roles in DNA structure, gene transcription and translation. YB-1 promotes chromosomal instability, and mammary gland transgenic expression induces tumors with 100% penetrance. YB-1 is linked to poor prognosis in breast carcinoma and is a...

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Bibliographic Details
Main Authors: Lovett, David H., Cheng, Sunfa, Cape, Leslie, Pollock, Allan S., Mertens, Peter R.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925540/
https://ncbi.nlm.nih.gov/pubmed/20599698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.06.104
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