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MT1-MMP hemopexin domain exchange with MT4-MMP blocks enzyme maturation and trafficking to the plasma membrane in MCF7 cells

The hemopexin-like domain of membrane-type matrix metalloproteinase-1 (MT1-MMP) enables MT1-MMP to form oligomers that facilitate the activation of pro-matrix metalloproteinase-2 (pro-MMP-2) at the cell surface. To investigate the role of the MT1-MMP hemopexin domain in the trafficking of MT1-MMP to...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Atkinson, Susan J., Roghi, Christian, Murphy, Gillian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Portland Press Ltd. 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1525013/
https://ncbi.nlm.nih.gov/pubmed/16686598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060243
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