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Tumour metastasis suppressor, nm23-beta, inhibits gelatinase A transcription by interference with transactivator Y-box protein-1 (YB-1).

Gelatinase A transcriptional regulation is the consequence of combinatorial interactions with key promoter and enhancer elements identified within this gene. A potent 40 bp enhancer response element, RE-1, located in the near 5' flanking regions of the rat and human gelatinase A genes drives hi...

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Detalles Bibliográficos
Autores principales: Cheng, Sunfa, Alfonso-Jaume, Maria Alexandra, Mertens, Peter R, Lovett, David H
Formato: Artigo
Lenguaje:Inglês
Publicado: 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222814/
https://ncbi.nlm.nih.gov/pubmed/12010125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020202
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