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Graded activation of the MEK1/MT1-MMP axis determines renal epithelial cell tumor phenotype
Activation of Raf/Ras/mitogen-activated protein kinase (MEK)/mitogen-activated protein kinase signaling and elevated expression of membrane type-1 matrix metalloproteinase (MT1-MMP) are associated with von Hippel–Lindau gene alterations in renal cell carcinoma. We postulated that the degree of MEK a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3220610/ https://ncbi.nlm.nih.gov/pubmed/21965271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr216 |
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