The Cancer-related Runx2 Protein Enhances Cell Growth and Responses to Androgen and TGFβ in Prostate Cancer Cells

Prostate cancer cells often metastasize to bone where osteolytic lesions are formed. Runx2 is an essential transcription factor for bone formation and suppresses cell growth in normal osteoblasts, but may function as an oncogenic factor in solid tumors (e.g., breast, prostate). Here, we addressed wh...

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Main Authors: van der Deen, Margaretha, Akech, Jackie, Wang, Tao, FitzGerald, Thomas J., Altieri, Dario C., Languino, Lucia R., Lian, Jane B., van Wijnen, Andre J., Stein, Janet L., Stein, Gary S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925394/
https://ncbi.nlm.nih.gov/pubmed/20082326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22463
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