Modulation of bitter taste perception by a small molecule hTAS2R antagonist

Human bitter taste is mediated by the hTAS2R family of G protein-coupled receptors [1-4]. The discovery of the hTAS2Rs enables the potential to develop specific bitter receptor antagonists that could be beneficial as chemical probes to examine the role of bitter receptor function in gustatory and no...

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Main Authors: Slack, Jay P., Brockhoff, Anne, Batram, Claudia, Menzel, Susann, Sonnabend, Caroline, Born, Stephan, Galindo, Maria Mercedes, Kohl, Susann, Thalmann, Sophie, Ostopovici-Halip, Liliana, Simons, Christopher T., Ungureanu, Ioana, Duineveld, Kees, Bologa, Cristian G., Behrens, Maik, Furrer, Stefan, Oprea, Tudor I., Meyerhof, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925244/
https://ncbi.nlm.nih.gov/pubmed/20537538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.04.043
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