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Substrate specific stimulation of NEIL1 by WRN but not the other human RecQ helicases
NEIL1, the mammalian homolog of Escherichia coli endonuclease VIII, is a DNA glycosylase that repairs ring-fragmented purines, saturated pyrimidines and several oxidative lesions like 5-hydroxyuracil, 5-hydroxycytosine etc. Previous studies from our laboratory have shown that Werner Syndrome protein...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2925176/ https://ncbi.nlm.nih.gov/pubmed/20346739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.02.012 |
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