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N-Alkyl-octahydroisoquinolin-1-one-8-carboxamides: Selective and Nonbasic κ-Opioid Receptor Ligands
[Image: see text] Herein, we report that N-alkyl-octahydroisoquinolin-1-one-8-carboxamides are a novel class of readily synthesized, selective κ-opioid receptor (KOR) ligands. A striking feature of this class of compounds is the absence of any basic nitrogen atoms. Many of these compounds have demon...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical Society
2010
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923850/ https://ncbi.nlm.nih.gov/pubmed/20729985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100040t |
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