mTOR Inhibition and Alloantigen-Specific Regulatory T Cells Synergize to Promote Long-Term Graft Survival in Immunocompetent Recipients

Minimization of immunosuppression and donor-specific tolerance to MHC-mismatched organ grafts are important clinical goals. The therapeutic potential of regulatory T cells (Treg) has been demonstrated, but conditions for optimizing their in vivo function post-transplant in nonlymphocyte-depleted hos...

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Detalhes bibliográficos
Main Authors: Raimondi, Giorgio, Sumpter, Tina L., Matta, Benjamin M., Pillai, Mahesh, Corbitt, Natasha, Vodovotz, Yoram, Wang, Zhiliang, Thomson, Angus W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923839/
https://ncbi.nlm.nih.gov/pubmed/20007530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900936
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