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Immunoregulatory Functions of mTOR Inhibition
The potent immunosuppressive action of rapamycin is commonly ascribed to inhibition of growth-factor-induced T-cell proliferation. However, it is now evident that the serine/threonine protein kinase mammalian target of rapamycin (mTOR) has an important role in the modulation of both innate and adapt...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2847476/ https://ncbi.nlm.nih.gov/pubmed/19390566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri2546 |
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