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Total Synthesis of Lehualide B by Allylic Alcohol–Alkyne Reductive Cross-Coupling
[Image: see text] The total synthesis of anticancer marine natural product lehualide B is described. Overall, the synthesis proceeds in just eight steps from a simple γ-pyrone, does not require the use of protecting groups, and delivers each nonconjugated trisubstituted alkene with high levels of st...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923668/ https://ncbi.nlm.nih.gov/pubmed/20681603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja104782u |
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