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Polyketide Assembly by Alkene–Alkyne Reductive Cross-Coupling: Spiroketals Through the Union of Homoallylic Alcohols

[Image: see text] A reaction sequence composed of regioselective formal hydroalkynylation, reductive ene-yne cross-coupling and oxidative cyclization has been developed to prepare stereochemically dense spiroketals. Overall, the chemistry defines a three-component coupling process for the union of t...

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Bibliografski detalji
Glavni autori: Canterbury, Daniel P., Micalizio, Glenn C.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892691/
https://ncbi.nlm.nih.gov/pubmed/20476790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja102888f
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