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Inhibition of sigma 1 receptor reduces N-methyl-d-aspartate induced neuronal injury in methamphetamine-exposed and -naive hippocampi

Acute and prolonged methamphetamine (METH) exposure has been reported to moderate the function of N-methyl-d-aspartate type glutamate receptors (NMDAr) in the hippocampus. These effects have been found to be associated with enhanced NMDAr-dependent release of Ca(2+) from IP(3)-sensitive intracellula...

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Bibliografski detalji
Glavni autori: Smith, Katherine J., Butler, Tracy R., Prendergast, Mark A.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923551/
https://ncbi.nlm.nih.gov/pubmed/20600592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.06.069
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