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Inhibition of sigma 1 receptor reduces N-methyl-d-aspartate induced neuronal injury in methamphetamine-exposed and -naive hippocampi
Acute and prolonged methamphetamine (METH) exposure has been reported to moderate the function of N-methyl-d-aspartate type glutamate receptors (NMDAr) in the hippocampus. These effects have been found to be associated with enhanced NMDAr-dependent release of Ca(2+) from IP(3)-sensitive intracellula...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923551/ https://ncbi.nlm.nih.gov/pubmed/20600592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.06.069 |
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