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Sigma ligands, but not N-methyl-d-aspartate antagonists, reduce levodopa-induced dyskinesias
Levodopa (l-DOPA) is the ‘gold standard’ to treat Parkinson's disease. Unfortunately, dyskinesias detract from its efficacy. Current dyskinesia treatments, including amantadine and dextromethorphan, are thought to work via N-methyl-d-aspartate (NMDA) antagonism, but this hypothesis has not been...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2845294/ https://ncbi.nlm.nih.gov/pubmed/18281903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e3282f3b0d1 |
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