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Multiple catalytic aldolase antibodies suitable for chemical programming

Chemical programming of nine murine antibodies with catalytic aldolase activity was examined using compounds, equipped with diketone or pro-vinyl ketone linkers that inhibit integrin adhesion receptor functions. The results showed that most Abs were programmed using the diketone compounds in a manne...

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Detalhes bibliográficos
Main Authors: Goswami, Rajib Kumar, Huang, Zheng-Zheng, Forsyth, Jane S., Felding-Habermann, Brunhilde, Sinha, Subhash C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923540/
https://ncbi.nlm.nih.gov/pubmed/19428247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.04.041
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