Chemically Programmed Antibodies Targeting Multiple Alpha(v) Integrins and Their Effects on Tumor-Related Functions in vitro

Integrins αvβ3 and αvβ6 are highly expressed on tumor cells and/or by the tumor vasculature of many human cancers, and represent promising targets for anti cancer therapy. Novel chemically programmed antibodies (cpAbs) targeting these integrins were prepared using the catalytic aldolase Antibody (Ab...

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Main Authors: Goswami, Rajib K., Bajjuri, Krishna M., Forsyth, Jane S., Das, Sanjib, Hassenpflug, Wolf, Huang, Zheng-Zheng, Lerner, Richard A., Felding-Habermann, Brunhilde, Sinha, Subhash C.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277862/
https://ncbi.nlm.nih.gov/pubmed/21774545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc2000879
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