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Noxa Mediates Hepatic Stellate Cell Apoptosis by Proteasome Inhibition
AIM: Induction of hepatic stellate cell (HSC) apoptosis is a viable therapeutic strategy to reduce liver fibrogenesis. Although BH3-only proteins of the Bcl-2 family trigger pro-apoptotic pathways, the BH3-only proteins mediating HSC apoptosis have not been well defined. Our aim, using proteasome in...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2922948/ https://ncbi.nlm.nih.gov/pubmed/20557369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1872-034X.2010.00668.x |
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