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Nitric Oxide Promotes Caspase-Independent Hepatic Stellate Cell Apoptosis Through the Generation of Reactive Oxygen Species

Hepatic stellate cells (HSCs) contribute to portal hypertension through multiple mechanisms that include collagen deposition, vasoconstriction, and regulation of sinusoidal structure. Under normal physiologic conditions, endothelial nitric oxide (NO) synthase–derived NO exerts paracrine effects on H...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Langer, Daniel A., Das, Amitava, Semela, David, Kang-Decker, Ningling, Hendrickson, Helen, Bronk, Steven F., Katusic, Zvonimir S., Gores, Gregory J., Shah, Vijay H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562502/
https://ncbi.nlm.nih.gov/pubmed/18459124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22285
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