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MITOCHONDRIA-DERIVED REACTIVE OXYGEN SPECIES MEDIATE CASPASE- DEPENDENT AND-INDEPENDENT NEURONAL DEATH

Mitochondrial dysfunction and oxidative stress are implicated in many neurodegenerative diseases. Mitochondria-targeted drugs that effectively decrease oxidative stress, protect mitochondrial energetics, and prevent neuronal loss may therefore lend therapeutic benefit to these currently incurable di...

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Détails bibliographiques
Publié dans:Mol Cell Neurosci
Auteurs principaux: Franklin, James L., McManus, Meagan J., Murphy, Michael P.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250393/
https://ncbi.nlm.nih.gov/pubmed/25239010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2014.09.002
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