DNA Methylation Profiles and Their Relationship with Cytogenetic Status in Adult Acute Myeloid Leukemia

BACKGROUND: Aberrant promoter DNA methylation has been shown to play a role in acute myeloid leukemia (AML) pathophysiology. However, further studies to discuss the prognostic value and the relationship of the epigenetic signatures with defined genomic rearrangements in acute myeloid leukemia are re...

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Autores principales: Alvarez, Sara, Suela, Javier, Valencia, Ana, Fernández, Agustín, Wunderlich, Mark, Agirre, Xabier, Prósper, Felipe, Martín-Subero, José Ignacio, Maiques, Alba, Acquadro, Francesco, Rodriguez Perales, Sandra, Calasanz, María José, Roman-Gómez, Jose, Siebert, Reiner, Mulloy, James C., Cervera, José, Sanz, Miguel Angel, Esteller, Manel, Cigudosa, Juan C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922373/
https://ncbi.nlm.nih.gov/pubmed/20808941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012197
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