DNA Methylation Profiles and Their Relationship with Cytogenetic Status in Adult Acute Myeloid Leukemia

BACKGROUND: Aberrant promoter DNA methylation has been shown to play a role in acute myeloid leukemia (AML) pathophysiology. However, further studies to discuss the prognostic value and the relationship of the epigenetic signatures with defined genomic rearrangements in acute myeloid leukemia are re...

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Detalhes bibliográficos
Main Authors: Alvarez, Sara, Suela, Javier, Valencia, Ana, Fernández, Agustín, Wunderlich, Mark, Agirre, Xabier, Prósper, Felipe, Martín-Subero, José Ignacio, Maiques, Alba, Acquadro, Francesco, Rodriguez Perales, Sandra, Calasanz, María José, Roman-Gómez, Jose, Siebert, Reiner, Mulloy, James C., Cervera, José, Sanz, Miguel Angel, Esteller, Manel, Cigudosa, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922373/
https://ncbi.nlm.nih.gov/pubmed/20808941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012197
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