DNA Methylation Profiles and Their Relationship with Cytogenetic Status in Adult Acute Myeloid Leukemia

BACKGROUND: Aberrant promoter DNA methylation has been shown to play a role in acute myeloid leukemia (AML) pathophysiology. However, further studies to discuss the prognostic value and the relationship of the epigenetic signatures with defined genomic rearrangements in acute myeloid leukemia are re...

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Главные авторы: Alvarez, Sara, Suela, Javier, Valencia, Ana, Fernández, Agustín, Wunderlich, Mark, Agirre, Xabier, Prósper, Felipe, Martín-Subero, José Ignacio, Maiques, Alba, Acquadro, Francesco, Rodriguez Perales, Sandra, Calasanz, María José, Roman-Gómez, Jose, Siebert, Reiner, Mulloy, James C., Cervera, José, Sanz, Miguel Angel, Esteller, Manel, Cigudosa, Juan C.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2010
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922373/
https://ncbi.nlm.nih.gov/pubmed/20808941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012197
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